Upper Respiratory Tract Levels of Severe Acute Respiratory Syndrome Coronavirus 2 RNA and Duration of Viral RNA Shedding Do Not Differ Between Patients With Mild and Severe/Critical Coronavirus Disease 2019 yilmaz2020upper
The authors reported longitudinal viral RNA loads from the nasopharynx/oropharynx in patients with mild and severe/critical coronavirus disease 2019 (COVID-19). They also investigated whether the duration of symptoms correlated with the duration of viral RNA shedding. A total of 56 patients were included.
Analytes
oropharyngealswab_SARSCoV2
The author collected serial upper respiratory tract samples (one nasopharyngeal swab and one oropharyngeal swab were put in a single collection tube with 1 mL of transport medium) for real-time PCR of SARS-CoV-2 RNA for all patients.
Biomarker: SARS-CoV-2
Specimen:
nasopharyngeal swab and oropharyngeal swab
Units: cycle threshold
Gene target: RdRp
Participants: 54
Negative samples: 80
Positive samples (not quantifiable): 0
Quantifiable samples: 269
Limit of quantification: unknown
Limit of detection: 40