Laboratory Diagnosis and Monitoring the Viral Shedding of SARS-CoV-2 Infection yang2020laboratory

This study involved 3552 clinical samples from 410 COVID-19 patients confirmed by Guangdong CDC. Oropharyngeal swabs, nasopharyngeal swabs and sputum samples were tested for upper respiratory tract infection, while bronchoalveolar lavage fluid (BALF) was tested for lower respiratory tract infection.

Analytes

upper_resp_tract

SARS-CoV-2 RNA ct value from evaluation of upper respiratory tract samples.

Biomarker: SARS-CoV-2
Specimen: nasopharyngeal swab, oropharyngeal swab, and sputum
Units: cycle threshold
Gene target: ORF1ab and N gene
Participants: 28
Negative samples: 174
Positive samples (not quantifiable): 0
Quantifiable samples: 102
Limit of quantification: unknown
Limit of detection: 38

lower_resp_tract

SARS-CoV-2 RNA ct value from evaluation of upper respiratory tract samples.

Biomarker: SARS-CoV-2
Specimen: bronchoalveolar lavage fluid
Units: cycle threshold
Gene target: ORF1ab and N gene
Participants: 21
Negative samples: 23
Positive samples (not quantifiable): 0
Quantifiable samples: 62
Limit of quantification: unknown
Limit of detection: 38