Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019 xing2020prolonged
This study characterized the dynamic profiles of SARS-CoV-2 shedding in respiratory and fecal specimens in three children with COVID-19. However, complete specimen test value data were available for only one child. A total of 19 oropharyngeal swab specimens and 17 fecal specimens were collected.
Analytes
stool_SARSCoV2
Presence of SARS-CoV-2 RNA was detected by RT-PCR in stool samples. The PCR assay simultaneously amplified two target genes of SARS-CoV-2 included open reading frame 1ab (ORF1ab) and nucleocapsid protein (N). A cycle threshold (Ct) value no more than 40 with evident amplification curve was considered as a positive test, and a value of 40 indicated the virus was molecularly undetectable.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
oropharyngeal_swab_SARSCoV2
Presence of SARS-CoV-2 RNA was detected by RT-PCR in oropharyngeal_swab samples. The PCR assay simultaneously amplified two target genes of SARS-CoV-2 included open reading frame 1ab (ORF1ab) and nucleocapsid protein (N). A cycle threshold (Ct) value no more than 40 with evident amplification curve was considered as a positive test, and a value of 40 indicated the virus was molecularly undetectable.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.