Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States team2020clinical
Respiratory, stool, serum, and urine specimens were submitted for SARS-CoV-2 real-time reverse-transcription polymerase chain reaction (rRT-PCR) testing, viral culture, and whole-genome sequencing. Only nasopharyngeal samples were included in this dataset. Data for the nasopharyngeal swab results were obtained from the combined dataset in the supplementary materials of Challenger et al. (2022), while attributes of hospitalized patients were obtained from the original paper.
Analytes
naso_swab_SARSCoV2_N_Ct
Cycle threshold (Ct) values were quantified using rRT-PCR targeting the N gene in nasopharyngeal swab samples.
Fitted by censored maximum likelihood. The red line is the median individual; the shaded region is the full range of a simulated cohort drawn from the fitted population, so it shows what simulating from this dataset would produce rather than a confidence interval, with dashed lines at the central 95%. Open triangles are non-detects, drawn at the censoring limit and entering the fit as "below this value" rather than being dropped. See the modelling methods for what these estimates do and do not support.