Distribution of Transmission Potential During Nonsevere COVID-19 Illness shrestha2020distribution

This study evaluated the transmission potential of COVID-19 by examining viral load over time. Over six weeks, 230 healthcare personnel underwent 528 tests at the Cleveland Clinic. Cycle threshold (Ct) values were obtained using RT-PCR targeting the N gene, and viral loads were calculated. Data were obtained from the combined dataset in the supplementary materials of Challenger et al. BMC Medicine (2022) 20:25 (https://doi.org/10.1186/s12916-021-02220-0).

Analytes

swab_SARSCoV2_N_Ct

Cycle threshold (Ct) values were quantified using RT-PCR targeting the N gene in nasopharyngeal swab samples.

Biomarker: SARS-CoV-2
Specimen: nasopharyngeal swab
Units: cycle threshold
Gene target: N
Participants: 230
Negative samples: 119
Positive samples (not quantifiable): 0
Quantifiable samples: 409
Limit of quantification: unknown
Limit of detection: 40