Clinical presentation, viral kinetics, and management of human monkeypox cases from New Delhi, India 2022 relhan2023clinical
Case series of five confirmed mpox (MPXV) cases from New Delhi, India (2022) without international travel history, describing clinical presentation and viral kinetics with serial sampling across multiple specimen types. This extraction contains Ct (cycle threshold) measurements from figure-derived CSV for two patients (PatientID 01 and 02) across oropharyngeal swab, nasopharyngeal swab, serum, urine, and lesion specimens at specific post-onset days.
Analytes
ct_oropharyngeal_swab
MPXV DNA detection by real-time PCR reported as cycle threshold (Ct) values in oropharyngeal swab (OPS) specimens; time is post-onset day (POD) of illness.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
ct_nasopharyngeal_swab
MPXV DNA detection by real-time PCR reported as cycle threshold (Ct) values in nasopharyngeal swab (NPS) specimens; time is post-onset day (POD) of illness.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
ct_serum
MPXV DNA detection by real-time PCR reported as cycle threshold (Ct) values in serum specimens; time is post-onset day (POD) of illness.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
ct_urine
MPXV DNA detection by real-time PCR reported as cycle threshold (Ct) values in urine specimens; time is post-onset day (POD) of illness.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
ct_lesion_base
MPXV DNA detection by real-time PCR reported as cycle threshold (Ct) values in lesion base specimens; time is post-onset day (POD) of illness.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
ct_lesion_fluid
MPXV DNA detection by real-time PCR reported as cycle threshold (Ct) values in lesion fluid specimens; time is post-onset day (POD) of illness.
Fitted by censored maximum likelihood. The red line is the median individual; the shaded region is the full range of a simulated cohort drawn from the fitted population, so it shows what simulating from this dataset would produce rather than a confidence interval, with dashed lines at the central 95%. Open triangles are non-detects, drawn at the censoring limit and entering the fit as "below this value" rather than being dropped. See the modelling methods for what these estimates do and do not support.
ct_lesion_roof
MPXV DNA detection by real-time PCR reported as cycle threshold (Ct) values in lesion roof specimens; time is post-onset day (POD) of illness.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
ct_lesion_crust
MPXV DNA detection by real-time PCR reported as cycle threshold (Ct) values in lesion crust specimens; time is post-onset day (POD) of illness.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.