Tecovirimat Resistance in an Immunocompromised Patient With Mpox and Prolonged Viral Shedding mertes2023tecovirimat
Letter reporting longitudinal PCR measurements in one immunocompromised adult patient with mpox receiving tecovirimat, including MPXV Ct values from an anal lesion and plasma over time, and plasma HIV viral load (gc/mL). Times are provided as day offsets relative to an unspecified reference event in the CSV.
Analytes
anal_lesion_mpxv_ct
MPXV PCR cycle threshold (Ct) measured from anal lesion specimen (as labeled in the figure-data CSV). Assay platform/gene target not provided in supplied content.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
plasma_mpxv_ct
MPXV PCR cycle threshold (Ct) measured in plasma (as labeled in the figure-data CSV). Assay platform/gene target not provided in supplied content.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
plasma_hiv_gc_ml
HIV viral load quantified in plasma in gene copies per mL (gc/mL), as provided in the figure-data CSV. Assay details not provided in supplied content.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.