Quantitative detection of norovirus excretion in pediatric patients with cancer and prolonged gastroenteritis and shedding of norovirus ludwig2008quantitative
Retrospective study of nine pediatric patients with hematologic/oncologic disorders and prolonged gastroenteritis, assessing prolonged fecal norovirus shedding measured by one-step real-time PCR and correlating quantitative shedding with clinical symptoms. Measurements are reported as fecal norovirus concentrations over time (days after symptom onset).
Analytes
stool_norovirus_viral_load
Quantitative norovirus detection/excretion measured in fecal samples using a one-step real-time PCR assay (as described in the abstract). CSV provides per-patient longitudinal quantitative values over days after symptom onset.
Fitted by censored maximum likelihood. The red line is the median individual; the shaded region is the full range of a simulated cohort drawn from the fitted population, so it shows what simulating from this dataset would produce rather than a confidence interval, with dashed lines at the central 95%. Open triangles are non-detects, drawn at the censoring limit and entering the fit as "below this value" rather than being dropped. See the modelling methods for what these estimates do and do not support.