Monkeypox Virus Infections in Southern Italy: Is There a Risk for Community Spread? loconsole2022monkeypox

Surveillance-based case series of 10 mpox (MPXV) cases identified in the Apulia region (Southern Italy) between 1 June and 1 August 2022. Multiple clinical specimens (skin lesion swab, nasopharyngeal swab, and whole blood) were tested using real-time PCR (Real-Star Orthopoxvirus PCR kit followed by an MPXV-specific confirmatory real-time PCR). The dataset reports quantification cycle (Cq) values or negative results, with sampling times reported as days from symptom onset.

Analytes

skin_lesion_swab

Mpox virus DNA real-time PCR quantification cycle (Cq) from skin lesion swab samples (Orthopoxvirus real-time PCR screening using Real-Star Orthopoxvirus PCR Kit with confirmatory MPXV-specific real-time PCR).

observations for skin_lesion_swab

Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.

Biomarker: mpox
Specimen: skin lesion
Units: cycle threshold
Participants: 10
Negative samples: 0
Positive samples (not quantifiable): 0
Quantifiable samples: 10
Limit of quantification: unknown
Limit of detection: unknown

nasopharyngeal_swab

Mpox virus DNA real-time PCR quantification cycle (Cq) from nasopharyngeal swab samples (Orthopoxvirus real-time PCR screening using Real-Star Orthopoxvirus PCR Kit with confirmatory MPXV-specific real-time PCR).

observations for nasopharyngeal_swab

Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.

Biomarker: mpox
Specimen: nasopharyngeal swab
Units: cycle threshold
Participants: 8
Negative samples: 2
Positive samples (not quantifiable): 0
Quantifiable samples: 6
Limit of quantification: unknown
Limit of detection: unknown

blood

Mpox virus DNA real-time PCR quantification cycle (Cq) from whole blood samples (Orthopoxvirus real-time PCR screening using Real-Star Orthopoxvirus PCR Kit with confirmatory MPXV-specific real-time PCR).

observations for blood

Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.

Biomarker: mpox
Specimen: blood
Units: cycle threshold
Participants: 9
Negative samples: 3
Positive samples (not quantifiable): 0
Quantifiable samples: 6
Limit of quantification: unknown
Limit of detection: unknown