Longitudinal Fecal Shedding of SARS-CoV-2, Pepper Mild Mottle Virus, and Human Mitochondrial DNA in COVID-19 Patients liu2024longitudinal
The authors measured SARS-CoV-2, pepper mild mottle virus (PMMoV), and human mitochondrial DNA (mtDNA) in longitudinal stool samples collected from 42 COVID-19 patients for up to 42 days after the first sample collection date. Abundances were quantified using Digital PCR assays targeting the N1 genes. The symptom data (e.g., fever, cough, short of breath, diarrhea, headache, loss of smell, loss of taste, etc.) is currently not included in this data.
Analytes
stool_SARSCoV2_N1
SARS-CoV-2 RNA genome copy concentration in stool samples. The concentration were quantified in genome copies per dry weight of stool.
Fitted by censored maximum likelihood. The red line is the median individual; the shaded region is the full range of a simulated cohort drawn from the fitted population, so it shows what simulating from this dataset would produce rather than a confidence interval, with dashed lines at the central 95%. Open triangles are non-detects, drawn at the censoring limit and entering the fit as "below this value" rather than being dropped. See the modelling methods for what these estimates do and do not support.
stool_PMMoV
PMMoV genome copy concentration in stool samples. The concentration were quantified in genome copies per dry weight of stool.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
stool_mtDNA
mtDNA genome copy concentration in stool samples. The concentration were quantified in genome copies per dry weight of stool.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.