Prolonged viral shedding in an immunocompromised Korean patient infected with hMPXV, sub-lineage B.1.3, with acquired drug resistant mutations during tecovirimat treatment lee2024prolonged
Case report from South Korea describing prolonged mpox (hMPXV) shedding in a 39-year-old male immunocompromised patient during tecovirimat treatment, with sequencing evidence of tecovirimat-associated resistance mutations (e.g., A290V, A288P) detected in different anatomical lesion/nasal samples over time.
Analytes
skin
Mpox virus PCR cycle threshold (Ct) measured from skin lesion-related specimen labeled ‘skin’ in figure-derived CSV.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
pubis
Mpox virus PCR cycle threshold (Ct) measured from pubis lesion-related specimen labeled ‘Pubis’ in figure-derived CSV.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
right_pubis
Mpox virus PCR cycle threshold (Ct) measured from right pubis lesion-related specimen labeled ‘Right Pubis’ in figure-derived CSV.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
left_forehead
Mpox virus PCR cycle threshold (Ct) measured from left forehead lesion-related specimen labeled ‘Left Forehead’ in figure-derived CSV.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
left_arm
Mpox virus PCR cycle threshold (Ct) measured from left arm lesion-related specimen labeled ‘Left Arm’ in figure-derived CSV.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
abdomen
Mpox virus PCR cycle threshold (Ct) measured from abdomen lesion-related specimen labeled ‘Abdomen’ in figure-derived CSV.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
penile
Mpox virus PCR cycle threshold (Ct) measured from penile lesion-related specimen labeled ‘Penile’ in figure-derived CSV.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
left_pubis
Mpox virus PCR cycle threshold (Ct) measured from left pubis lesion-related specimen labeled ‘Left Pubis’ in figure-derived CSV.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
left_buttock
Mpox virus PCR cycle threshold (Ct) measured from left buttock lesion-related specimen labeled ‘Left Buttock’ in figure-derived CSV.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
nose
Mpox virus PCR cycle threshold (Ct) measured from nose lesion-related specimen labeled ‘Nose’ in figure-derived CSV.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.