Clinical and virological characteristics of viral shedding in children with norovirus gastroenteritis lee2022clinical

Study of pediatric norovirus gastroenteritis cases admitted to Chang Gung Memorial Hospital (Taiwan) during 2017–2018. Norovirus was quantified from fecal specimens using a SYBR Green-based real-time qRT-PCR method and genotypes were characterized by sequencing. CSV figure data provide norovirus concentrations over days after symptom onset, reported either as gc/mL (many participants) or gc/wet gram (one immunocompromised patient with prolonged shedding).

Analytes

gc_ml

Norovirus RNA concentration measured by SYBR Green-based real-time quantitative RT-PCR (qRT-PCR) from fecal specimen extract; values reported as gene copies per mL (gc/mL).

observations for gc_ml

Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.

Biomarker: norovirus
Specimen: stool
Units: gc/mL
Gene target: RdRp
Participants: 54
Negative samples: 6
Positive samples (not quantifiable): 0
Quantifiable samples: 48
Limit of quantification: unknown
Limit of detection: unknown

gc_wet_gram

Norovirus RNA concentration measured by SYBR Green-based real-time quantitative RT-PCR (qRT-PCR) from stool; values reported as gene copies per wet gram (gc/wet gram).

observations for gc_wet_gram

Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.

Biomarker: norovirus
Specimen: stool
Units: gc/wet gram
Gene target: RdRp
Participants: 1
Negative samples: 0
Positive samples (not quantifiable): 0
Quantifiable samples: 10
Limit of quantification: unknown
Limit of detection: 50