Densely sampled viral trajectories suggest longer duration of acute infection with B.1.1.7 variant relative to non-B.1.1.7 SARS-CoV-2 kissler2021densely

This study analyzed densely sampled longitudinal RT-qPCR data from 65 individuals infected with SARS-CoV-2, including 7 infected with the B.1.1.7 (Alpha) variant, using each person’s lowest Ct value as the reference event time point. Inclusion criteria required each individual to have at least 5 positive PCR tests (Ct < 40), including at least one with Ct < 35. Ct value were collected using the Roche cobas target 1 assay and converted to estimated RNA viral concentrations via a standard curve and log-linear transformation.

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