Viral kinetics of SARS-CoV-2 in asymptomatic carriers and presymptomatic patients kimse2020viral
The authors measured SARS-CoV-2 in longitudinal oropharyngeal swab samples collected from 71 COVID-19 patients between February 4 and April 7, 2020.
Analytes
oropharyngealswab_SARSCoV2_symptomatic
SARS-CoV-2 RNA genome copy concentration in oropharyngeal swab samples. Ct = 35 is the cut-off for a positive result and Ct = 40 is a negative sample; Ct = 40 was the limit of detection.
Fitted by censored maximum likelihood. The red line is the median individual; the shaded region is the full range of a simulated cohort drawn from the fitted population, so it shows what simulating from this dataset would produce rather than a confidence interval, with dashed lines at the central 95%. Open triangles are non-detects, drawn at the censoring limit and entering the fit as "below this value" rather than being dropped. See the modelling methods for what these estimates do and do not support.
oropharyngealswab_SARSCoV2_asymptomatic
SARS-CoV-2 RNA genome copy concentration in oropharyngeal swab samples.Ct = 35 is the cut-off for a positive result and Ct = 40 is a negative sample; Ct = 40 was the limit of detection.
Fitted by censored maximum likelihood. The red line is the median individual; the shaded region is the full range of a simulated cohort drawn from the fitted population, so it shows what simulating from this dataset would produce rather than a confidence interval, with dashed lines at the central 95%. Open triangles are non-detects, drawn at the censoring limit and entering the fit as "below this value" rather than being dropped. See the modelling methods for what these estimates do and do not support.