Viral Load Kinetics of SARS-CoV-2 Infection in First Two Patients in Korea kim2020viral
The authors present viral load kinetics for the first two confirmed COVID-19 patients with mild to moderate illness in Korea. Swabs, sputum, serum, plasma, urine, and stool samples were collected throughout the illness. Cycle threshold (Ct) values were quantified using rRT-PCR targeting the RdRp and E genes. Data were obtained from the supplementary material.
Analytes
sputum_SARSCoV2_RdRp_VL
Cycle threshold (Ct) values were quantified using rRT-PCR targeting the RdRp gene in sputum samples. Ct values were then converted into estimated viral copies per mL, with a detection limit of 2,690 copies/mL. The RNA copy number was calculated by the authors using a standard curve derived from Ct values of plasmid DNA, as noted in the supplementary material.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
swab_SARSCoV2_RdRp_VL
Cycle threshold (Ct) values were quantified using rRT-PCR targeting the RdRp gene in swab samples. Ct values were then converted into estimated viral copies per mL, with a detection limit of 2,690 copies/mL. The RNA copy number was calculated by the authors using a standard curve derived from Ct values of plasmid DNA, as noted in the supplementary material.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
swab_SARSCoV2_E_Ct
Cycle threshold (Ct) values were quantified using rRT-PCR targeting the E gene in swab samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
sputum_SARSCoV2_E_Ct
Cycle threshold (Ct) values were quantified using rRT-PCR targeting the E gene in sputum samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
stool_SARSCoV2_E_Ct
Cycle threshold (Ct) values were quantified using rRT-PCR targeting the E gene in stool samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
stool_SARSCoV2_RdRp_Ct
Cycle threshold (Ct) values were quantified using rRT-PCR targeting the RdRp gene in stool samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
sputum_SARSCoV2_RdRp_Ct
Cycle threshold (Ct) values were quantified using rRT-PCR targeting the RdRp gene in sputum samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
swab_SARSCoV2_RdRp_Ct
Cycle threshold (Ct) values were quantified using rRT-PCR targeting the RdRp gene in swab samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.