Sequential Analysis of Viral Load in a Neonate and Her Mother Infected With Severe Acute Respiratory Syndrome Coronavirus 2 han2020sequential
The study reports SARS-CoV-2 viral loads in different specimen types for a neonate and her mother diagnosed on 2020-03-20. The study includes nasopharyngeal, oropharyngeal, stool, plasma, saliva, and urine samples. Viral loads were extracted manually from Figure 1 using WebPlotDigitizer.
Analytes
nasopharynx_E
SARS-CoV-2 RNA gene copy concentration in nasopharynx samples.
Biomarker: SARS-CoV-2
Specimen:
nasopharyngeal swab
Units: gc/mL
Gene target: E
Participants: 1
Negative samples: 3
Positive samples (not quantifiable): 0
Quantifiable samples: 4
Limit of quantification: unknown
Limit of detection: 5,700.00
oropharynx_E
SARS-CoV-2 RNA gene copy concentration in oropharynx samples.
Biomarker: SARS-CoV-2
Specimen:
oropharyngeal swab
Units: gc/mL
Gene target: E
Participants: 1
Negative samples: 2
Positive samples (not quantifiable): 0
Quantifiable samples: 4
Limit of quantification: unknown
Limit of detection: 5,700.00
NPSOPS_E
SARS-CoV-2 RNA gene copy concentration in oropharynx and nasopharynx samples.
Biomarker: SARS-CoV-2
Specimen:
nasopharyngeal swab and oropharyngeal swab
Units: gc/mL
Gene target: E
Participants: 1
Negative samples: 5
Positive samples (not quantifiable): 0
Quantifiable samples: 2
Limit of quantification: unknown
Limit of detection: 5,700.00
plasma_E
SARS-CoV-2 RNA gene copy concentration in plasma samples.
Biomarker: SARS-CoV-2
Specimen:
plasma
Units: gc/mL
Gene target: E
Participants: 2
Negative samples: 2
Positive samples (not quantifiable): 0
Quantifiable samples: 2
Limit of quantification: unknown
Limit of detection: 5,700.00
saliva_E
SARS-CoV-2 RNA gene copy concentration in saliva samples.
Biomarker: SARS-CoV-2
Specimen:
saliva
Units: gc/mL
Gene target: E
Participants: 1
Negative samples: 1
Positive samples (not quantifiable): 0
Quantifiable samples: 2
Limit of quantification: unknown
Limit of detection: 5,700.00
urine_E
SARS-CoV-2 RNA gene copy concentration in urine samples.
Biomarker: SARS-CoV-2
Specimen:
urine
Units: gc/mL
Gene target: E
Participants: 2
Negative samples: 3
Positive samples (not quantifiable): 0
Quantifiable samples: 6
Limit of quantification: unknown
Limit of detection: 5,700.00
sputum_E
SARS-CoV-2 RNA gene copy concentration in sputum samples.
Biomarker: SARS-CoV-2
Specimen:
sputum
Units: gc/mL
Gene target: E
Participants: 1
Negative samples: 4
Positive samples (not quantifiable): 0
Quantifiable samples: 2
Limit of quantification: unknown
Limit of detection: 5,700.00
stool_E
From manuscript: “Viral RNA was detected using the PowerChek 2019-nCoV real-time polymerase chain reaction kit (Kogene Biotech, Seoul, Korea) for amplification of the E gene and the RNA-dependent RNA polymerase region of the ORF1b gene, and quantified with a standard curve that was constructed using in vitro transcribed RNA provided from the European Virus Archive.” However, data reported in Figure 1 explicitly refer to the E gene target.