Sequential Analysis of Viral Load in a Neonate and Her Mother Infected With Severe Acute Respiratory Syndrome Coronavirus 2 han2020sequential
The study reports SARS-CoV-2 viral loads in different specimen types for a neonate and her mother diagnosed on 2020-03-20. The study includes nasopharyngeal, oropharyngeal, stool, plasma, saliva, and urine samples. Viral loads were extracted manually from Figure 1 using WebPlotDigitizer.
Analytes
nasopharynx_E
SARS-CoV-2 RNA gene copy concentration in nasopharynx samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
oropharynx_E
SARS-CoV-2 RNA gene copy concentration in oropharynx samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
NPSOPS_E
SARS-CoV-2 RNA gene copy concentration in oropharynx and nasopharynx samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
plasma_E
SARS-CoV-2 RNA gene copy concentration in plasma samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
saliva_E
SARS-CoV-2 RNA gene copy concentration in saliva samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
urine_E
SARS-CoV-2 RNA gene copy concentration in urine samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
sputum_E
SARS-CoV-2 RNA gene copy concentration in sputum samples.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.
stool_E
From manuscript: “Viral RNA was detected using the PowerChek 2019-nCoV real-time polymerase chain reaction kit (Kogene Biotech, Seoul, Korea) for amplification of the E gene and the RNA-dependent RNA polymerase region of the ORF1b gene, and quantified with a standard curve that was constructed using in vitro transcribed RNA provided from the European Virus Archive.” However, data reported in Figure 1 explicitly refer to the E gene target.
Measurements only — no shedding model is fitted to this analyte, usually because it is sampled once per participant, leaving no trajectory to fit, or because nothing was ever detected. Open triangles are non-detects, drawn at the assay's censoring limit. See the modelling methods for what these estimates do and do not support.