Hydroxychloroquine and azithromycin as a treatment of COVID-19:results of an open-label non-randomized clinical trial gautret2020hydroxychloroquine
This study evaluated the effect of hydroxychloroquine on respiratory viral loads. Six patients were asymptomatic, 22 exhibited upper respiratory tract infection symptoms, and eight showed lower respiratory tract infection symptoms. Only 19 patients with a known onset of symptoms were included in the analysis below. Data for the nasopharyngeal swab results were obtained from the combined dataset in the supplementary materials of Challenger et al. (2022). Attributes of drug treatments were sourced from the supplementary materials of the original paper.
Analytes
nasopharyngeal_swab_SARSCoV2_Ct
Cycle threshold (Ct) values targeting the E gene in nasopharyngeal swab samples.
Biomarker: SARS-CoV-2
Specimen:
nasopharyngeal swab
Units: cycle threshold
Participants: 19
Negative samples: 44
Positive samples (not quantifiable): 0
Quantifiable samples: 82
Limit of quantification: unknown
Limit of detection: 35