Adenovirus infection and treatment with cidofovir in children after liver transplantation engelmann2009adenovirus
Retrospective study of pediatric liver transplant recipients monitored for adenovirus (ADV) DNAemia by quantitative real-time PCR in serum up to 24 weeks after transplant. The provided CSV contains longitudinal serum ADV PCR results (negative/quantified) at specified days post-transplant for 15 individual patients, with some patients symptomatic and with reported ADV genotypes for a subset (e.g., HAdV-C2, HAdV-C6). The original paper lists patient 9’s adenovirus type as “A41”, which is a typo – there is no adenovirus type A41. It is unclear whether the intended type was F41 or A31, so genotype is marked unknown rather than guessing.
Analytes
serum_adenovirus_viral_load
Quantitative real-time PCR (qPCR) measurement of adenovirus (ADV) DNA in serum from pediatric liver transplant recipients, reported as copies per mL serum.
Fitted by censored maximum likelihood. The red line is the median individual; the shaded region is the full range of a simulated cohort drawn from the fitted population, so it shows what simulating from this dataset would produce rather than a confidence interval, with dashed lines at the central 95%. Open triangles are non-detects, drawn at the censoring limit and entering the fit as "below this value" rather than being dropped. See the modelling methods for what these estimates do and do not support.