chen2024clinicalCase series from Taiwan (2023 mpox outbreak) reporting viral kinetics (PCR Ct values) across multiple specimen types (oropharyngeal/throat swab, vesicle swab, urethral swab, rectal swab) in mpox cases, including people with HIV and tecovirimat treatment. This extraction covers CSV batch 1/4 with repeated sampling per patient over days since a clinical reference timepoint (not specified in the provided excerpt).
oropharyngeal_swab
Mpox virus DNA detection by PCR reported as cycle threshold (Ct) value from oropharyngeal (throat) swab (CSV rows where specimen=throat swab). Assay details (platform/gene target) not provided in the excerpted data.
Fitted by censored maximum likelihood. The red line is the median individual; the shaded region is the full range of a simulated cohort drawn from the fitted population, so it shows what simulating from this dataset would produce rather than a confidence interval, with dashed lines at the central 95%. Open triangles are non-detects, drawn at the censoring limit and entering the fit as "below this value" rather than being dropped. See the modelling methods for what these estimates do and do not support.
vesicle_swab
Mpox virus DNA detection by PCR reported as cycle threshold (Ct) value from vesicle swab. Assay details (platform/gene target) not provided in the excerpted data.
Fitted by censored maximum likelihood. The red line is the median individual; the shaded region is the full range of a simulated cohort drawn from the fitted population, so it shows what simulating from this dataset would produce rather than a confidence interval, with dashed lines at the central 95%. Open triangles are non-detects, drawn at the censoring limit and entering the fit as "below this value" rather than being dropped. See the modelling methods for what these estimates do and do not support.
urethra_swab
Mpox virus DNA detection by PCR reported as cycle threshold (Ct) value from urethral swab. Assay details (platform/gene target) not provided in the excerpted data.
Fitted by censored maximum likelihood. The red line is the median individual; the shaded region is the full range of a simulated cohort drawn from the fitted population, so it shows what simulating from this dataset would produce rather than a confidence interval, with dashed lines at the central 95%. Open triangles are non-detects, drawn at the censoring limit and entering the fit as "below this value" rather than being dropped. See the modelling methods for what these estimates do and do not support.
rectal_swab
Mpox virus DNA detection by PCR reported as cycle threshold (Ct) value from rectal swab. Assay details (platform/gene target) not provided in the excerpted data.
Fitted by censored maximum likelihood. The red line is the median individual; the shaded region is the full range of a simulated cohort drawn from the fitted population, so it shows what simulating from this dataset would produce rather than a confidence interval, with dashed lines at the central 95%. Open triangles are non-detects, drawn at the censoring limit and entering the fit as "below this value" rather than being dropped. See the modelling methods for what these estimates do and do not support.